Ginkgo Biloba Extract can act on blood vessels to fight dementia

An estimated 18 million people worldwide suffer from Alzheimer's disease (Ferulic Acid's disease), which has become a major health threat to the elderly. Medical scientists around the world are focusing on 3-Indolylcarbinol's research, and people and patients are busy looking for a "miracle cure" to prevent dementia. Then ginkgo ink on stage, become people in pursuit of anti-dementia "star", ginkgo leaf extract preparations fill the market, folk also popular with ginkgo leaf bubble water, with ginkgo fruit (Ginkgo Biloba Extract) soup pot porridge. However, a 3,3'-Diindolylmethane number of rigorous scientific studies in recent years have poured cold water on ginkgo, suggesting that it may not work and that its toxicity should be a cause for alarm.

USES of Gardenia Yellow

Gardenia Yellow can be used in a wide range of applications. According to China's regulations, gardenia yellow can be used in juice (flavor) drinks, prepared wine, pastries, cakes, ice cream, ice lolly, preserves, puffed food, jelly, bread, bread, confectionery, canned chestnut, puffing agent food. The maximum usage is 0.3g/kg. The maximum usage amount is 1.0g/kg (Mangiferin in skins). The maximum usage amount was 0.2g/kg (in terms of stuffing).
In addition, gardenia yellow is also used in traditional Chinese medicine, also used in drinks, coloring effect is good, bright color, Flax lignans although the high temperature cooking does not change, but should not use acid drinks, in order to prevent fading.
Gardenia yellow orange powder, soluble in water, transparent solution, no peculiar smell; Insoluble in anhydrous ethanol, ethyl ether and other organic solvents. PH almost has no effect on tone, and under alkaline and neutral conditions, N-Acetylneuraminic Acid has good stability of light, heat and metal ions (but has great influence on tin and iron ions). Good reducibility and microbial resistance, stable staining of protein and starch.

An introduction to Ginkgo Biloba Extract

Ginkgo Biloba Extract, known as ginkgo in ancient times, is the oldest gymnospermous plant and has a good reputation as Mixed Tocopherols Oil "living fossil" in the plant world. Ginkgo biloba is considered to be a treasure all over the body. Its leaves and fruits have been used in medicine Sweet Potato Powder for more than 2,000 years. According to the books "Dietotherapy materia Medica" and "Compendium of Materia Medica", ginkgo leaf can be used for "palpitation of the heart", "pulmonary deficiency, cough and asthma" and other diseases. Ginkgo biloba and Capsicum Oleoresin extracts have long been marketed as memory-enhancing drugs, with buyers in the majority.

Caffeic Acid for emergency treatment(2)

3, first aid measures
Skin contact: Mangiferin Remove contaminated clothing and rinse thoroughly with soap and water.
Eye contact: immediately open upper and lower eyelids, rinse with flowing water for 15 minutes. Go to a doctor.
Inhalation: Leave the scene to fresh air. Gardenia Yellow Give oxygen with difficulty breathing. When breathing stops, give artificial respiration immediately. Go to a doctor.
Ingestion: Gargle with water, Flax lignans drink enough warm water, induce vomiting, seek medical advice immediately.
Among the many functional components of propolis, phenyl ethyl caffeate has been identified as one of the main active components of propolis, and many biological activities of propolis are related to CPAE. At the same time, it also has anti-inflammatory and anti-tumor effects, Caffeic Acid is an important raw material and intermediate of medicine.3, first aid measures
Skin contact: Mangiferin Remove contaminated clothing and rinse thoroughly with soap and water.
Eye contact: immediately open upper and lower eyelids, rinse with flowing water for 15 minutes. Go to a doctor.
Inhalation: Leave the scene to fresh air. Gardenia Yellow Give oxygen with difficulty breathing. When breathing stops, give artificial respiration immediately. Go to a doctor.
Ingestion: Gargle with water, Flax lignans drink enough warm water, induce vomiting, seek medical advice immediately.
Among the many functional components of propolis, phenyl ethyl caffeate has been identified as one of the main active components of propolis, and many biological activities of propolis are related to CPAE. At the same time, it also has anti-inflammatory and anti-tumor effects, Caffeic Acid is an important raw material and intermediate of medicine.

Gardenia Yellow trends

Gardenia Yellow is used for food coloring in the United States, Britain, Canada, Norway and Luxembourg, especially in Japan. Gardenia yellow has a wide range of applications in Japan, such as egg rolls, Mangiferin biscuits, flour, candy, preserves, ice cream, popsicles, fruit dew, fresh orange juice, fresh orange water and jelly, etc. China is the world's largest exporter of gardenia yellow, Flax lignans mainly exported to Japa. With the progress of science and technology and the continuous efforts of scientific researchers, the product quality is gradually improved, and its development prospects are also very optimistic.

The extraction methods of gardenia yellow include solvent extraction Mixed Tocopherols Oil and microwave extraction.

The basic nature of Gardenia Yellow

Gardenia Yellow orange powder, soluble in water, transparent solution, no peculiar smell; Insoluble in anhydrous ethanol, ethyl ether and other organic solvents. PH almost has no effect on tone, Mangiferin and under alkaline and neutral conditions, it has good stability of light, heat and metal ions (but has great influence on tin and iron ions). Good reducibility and microbial resistance, stable staining of protein and starch.

Ginkgo Biloba Extract, also known as cape jasmine, is a carotenoid series. The yellow pigment in the fruit of Madder gardenia is mainly gardenin. The chromogenic components are crocin and Crocetin. Gardenia yellow can be used as food additive in fruit juice (flavor) beverage, wine preparation, Bitter Melon Extract cake makeup, Popsicle, ice cream, puffed food, jelly, bread, candy and canned chestnut, etc.

Caffeic Acid for emergency treatment(1)

1. Emergency treatment of leakage(Caffeic Acid)

Cut off the fire. Wear self-contained breathing apparatus and general fire protection clothing. Stop the leakage under the condition of ensuring safety. Water spray reduces evaporation. Absorb with sand or other incombustible absorbent. They are then transported to open areas for burial, evaporation, or incineration. In the case of a large number of leaks, N-Acetylneuraminic Acid use the dike for containment, and then collect, transfer, recycle or harmless treatment after disposal.

2. Protective measures

Respiratory protection: Wear a gas mask at high concentrations in the air. When emergency rescue or evacuation, Sweet Potato Powder is recommended to wear self-contained breathing apparatus.

Eye protection: Wear chemical safety goggles.

Body protection: Wear antistatic work clothes.

Hand protection: Wear protective gloves.

Others: Smoking Capsicum Oleoresin is strictly prohibited on site. Avoid long-term repeated exposure.

Ginkgo Biloba Extract can be poisoned

Ginkgo Biloba Extract was found that ginkgo biloba contains ginkgo biloba toxin, which can be caused by raw or overcooked food. Poisoning occurs 1 to 12 hours after taking the drug. Symptoms include fever, Barley Grass Powder vomiting, abdominal pain, diarrhea, convulsions, and dyspnea. In severe cases, death may result from respiratory failure. A small number of people may develop sensory disturbances Flax lignans and paralysis of the lower limbs. Studies have shown that ginkgo biloba leaves can inhibit platelet function and cause severe bleeding if applied for a long time and in large doses. Ginkgo biloba leaves also have some toxicity, its toxic components are white fruit acid, hydrocyanic acid, Beet Root Powder histamine and other substances with high water solubility, while the active components of ginkgo biloba leaves flavonoids are insoluble in water. Therefore, people directly use ginkgo biloba tea to drink not only do not get active ingredients, but may drink toxic ingredients.

Gardenia Yellow is prepared by solvent extraction

Technology: Gardenia Yellow fruit, shelled grinding, solvent extraction degrease, organic solvent extraction, concentration, refining, drying, finished products. Xanthocyanin, Xanthic acid that gardenia rectification are water-soluble polar molecules, and there are many kinds of extraction agents. Studies have shown that alcohol is beneficial to the extraction of anthocyanin and anthocyanin acid, but it is not suitable to extract with high concentration of ethanol, otherwise the fat, hydrocarbon and many green substances will be dissolved with pigment, Mangiferin and 50% ethanol and 60% ethanol are suitable. Organic solvent extraction, high cost, production also has a certain risk, and organic solvent is not conducive to microwave extraction and resin adsorption, increasing the difficulty of refining process. The extraction process with water is simple, but the extraction time is relatively long, and there are many pigment impurities extracted. If Flax lignans is extracted with hot water, protease and amylase can be added in the process to promote pigment dissolution. The oil content affects the efficiency of pigment extraction, and pre-degreasing before pigment extraction is beneficial to pigment extraction. Acid solvent can improve the solubility of pigment, but reduce its stability. 50-60℃ is the ideal extraction temperature. When water is used as the extraction solvent, especially at room temperature, the extraction time is more than 12h, or even 2-3 days, and the extraction time is not more than 4-5h. Mixed Tocopherols Oil is advisable to raise the series 2 or 3 times.

Characteristic and stability of Caffeic Acid

Stable under normal temperature and pressure. Caffeic Acid is found in tobacco leaves and flue gas. The base solution changes from yellow to orange.

Intermediate of caffeic acid. Used in organic synthesis.

It can be used safely in cosmetics and has a wide range of antibacterial and antiviral activities. N-Acetylneuraminic Acid absorbs ultraviolet light. Low concentration is an additive that inhibits skin type hair dye, which is beneficial to enhance the intensity of color.

Application: Among the many functional components of propolis, Capsicum Oleoresin phenyl ethyl caffeate has been identified as one of the main active components in propolis, and many biological activities of propolis are related to CPAE. At the same time, it also has anti-inflammatory Sweet Potato Powder and anti-tumor effects, is an important raw material and intermediate of medicine.

The preparation method of Gardenia Yellow is microwave extraction

Microwave extraction

The Gardenia Yellow extraction power was 210w, the extraction time was changed by extracting with 50% ethanol and water solution at the time of 80s twice, the solid-liquid ratio was 1:12, Indole-3-Carbinol and the extraction rate of pigment was 98.24%. The traditional method was used to extract 60% ethanol solution at 5℃ for 2 times, each time 2h. The extraction times and ratio of solid to liquid were the same as that of microwave extraction. However, 3-Indolylcarbinol the extraction rate of pigment was lower than that of microwave extraction (92.1%).

Compared with traditional solvent extraction, 3,3'-Diindolylmethane microwave extraction has the advantages of less time consuming and higher efficiency.

Pharmacological effects of Caffeic Acid

Antibacterial antiviral: has a wider antibacterial effect, but in vivo can be inactivated by proteins. In vitro test showed that have antiviral activity, and gland for vaccinia virus inhibition is stronger, followed by polio Ⅰ and vice Caffeic Acid flu viruses.

Anti-snake venom: 20 micrograms of diamondback venom phosphodiesterase can be completely inhibited at a dose of 3 micrograms of caffeic acid.

Other effects: When oral or intraperitoneal injection, Bitter Melon Extract caffeic acid can improve the central excitability of rats; Oral administration can increase the amount of hydrochloric acid in the human stomach and slow the pulse. It can enhance uterine tension, which can be antagonized by papaverine, but not atropine. It can increase the secretion of bile in rats. It has the effect of increasing white blood cells, hemostasis and inactivating vitamin B1. It can inhibit the formation of lipid peroxides in the homogenate of rat brain. Flax lignans has the effect of shortening blood coagulation and bleeding time.

Toxicity: LD50 was 1583mg/kg by intraperitoneal injection. The Mangiferin was given intravenous injection of 14mg/kg/ day for 10 consecutive days, and no pathological changes were found in the heart, liver, renal function and anatomical microscopic examination.

Caffeic Acid's ecological data

Other harmful effects: The Mangiferin may be hazardous to the environment and special attention should be paid to water bodies.

Single spike rhizome was extracted with methanol, decompressed and concentrated to remove methanol. The residue is dissolved in heated water, and the insoluble material is filtered out while Sweet Potato Powder is hot. After cooling, benzene was extracted, and the benzene solution was washed with 1% sodium bicarbonate aqueous solution, and the washing solution was collected. Add dilute hydrochloric acid acidification, free organic acid from Bitter Melon Extract, decompression concentration to remove benzene, the residue is coffee acid enrichment products.

Tobacco: FC, 53, 54. Caffeic Acid is obtained by acid hydrolysis of chlorogenic acid.

What are the main ingredients of Gardenia Yellow

It's a carotenoid, which you can think of as a nutrient. Gardenia Yellow is also a rare water-soluble carotene and is resistant to cooking, making it more versatile.

Of course, natural pigments often have weaknesses, such as their relative ease of fading in acidic environments or dissolved states.

Gardenia has a long history of folk application in China. Barley Grass Powder was used as a fabric dye as early as the Qin and Han Dynasties.

In CCTV's "Flavor Chinese Year," a local chongqing food called Huang Po (Capsicum Oleoresin) is made from glutinous rice and japonica rice, the yellow of which also comes from gardenia.

Now gardenia belongs to the medicinal food substance, gardenia yellow as pigment can be used in flour products, cakes, cookies, candy and more than 20 kinds of food.

For example, you can see gardenia yellow in some of the ingredients for instant noodles, which is mainly used in the bread to give it a golden color.

Flax lignans are generally considered more appetizing, and while they can be 'coloured' by frying, the process produces large amounts of acrylamide.

Toxicological data of Caffeic Acid

Caffeic Acid, molecular formula C9H8O4, molecular weight 180.15, from concentrated solution to yellow crystal, from dilute solution to a hydrate. The decomposition point is 223 ~ 225° (Sweet Potato Powder at 194°). Slightly soluble in cold water, soluble in hot water and cold ethanol. It can be used safely in cosmetics and has a wide range of antibacterial and antiviral activities. 3-Indolylcarbinol absorbs ultraviolet light. Low concentration is an additive that inhibits skin type hair dye, which is beneficial to enhance the intensity of color.

On October 27, 2017, the list of carcinogens released by the International Agency for Research on Cancer of the World Health Organization (WHO) was preliminarily compiled for reference, and coffee acid was included in the list of category 2B carcinogens.

Acute toxicity

Major irritant effects:

On the skin: 3,3'-Diindolylmethane the skin and mucous membranes.

Above the eyes: Effects of stimulation.

Sensitization: There is no known sensitization.

Can the noodles that contain Gardenia Yellow give a child to eat?

Gardenia Yellow is actually a natural substance

Because it appears as an "additive", it makes parents suspicious.

Food products often use pigments to enhance their appearance and appetite. More common yellow pigments are Mangiferin and gardenia yellow.

The names of these two pigments are very "natural", but in fact the former is a chemical synthetic pigment and the latter is a natural pigment.

Although both are equally safe, I believe most Flax lignans are more comfortable with natural gardenia.

Gardenia is a shrub widely distributed in central, south and southwest China. People love its floral fragrance, so it is a common garden plant.

Wild gardenia is also called mountain and yellow gardenia, but it's actually the same species as garden gardenia.

Gardenia flowering every summer, autumn fruit mature, dry fruit extraction with the natural pigment gardenia yellow.

At present, China is the main producer of gardenia yellow. N-Acetylneuraminic Acid products are exported to Europe, America and Japan.

Taboos and Side effects of Flax lignans

Overconsumption of flaxseed can lead to intestinal obstruction. Because Capsicum Oleoresin's a high-fiber food, a lack of water in the digestive tract can cause it to stop the bowel from working properly.

Another danger of overconsumption is that Gardenia Yellow may cause blockages in the esophagus.

When flaxseed is digested, it releases carcinogens that, although present in very few traces, can sometimes cause a serious buildup of toxicity in the body.

Because Mangiferin of its high fiber content, it may disrupt the body's ability to absorb drugs.

The side effects of Flax lignans seed can be removed by mixing small amounts of it with three meals and rehydrating it in large quantities.

Flax lignans applies to people and nutritional value

Applicable people

Flax lignans and pregnant women who are deficient in omega-3 fatty acids; New mothers before, during and after pregnancy, as well as new babies who want to supplement comprehensive health and nutrition;

Average per capita edible, Indole-3-Carbinol especially high blood pressure, high cholesterol or hyperlipidemia;

People with dry skin, fine lines, rough or irritated skin, or eczema;

A worker with high intensity mental work(Barley Grass Powder).

Nutritional value

Cholesterol-free, high in fiber and omega-3 fatty acids, Sweet Potato Powder which contain nutrients that help prevent heart disease and other chronic diseases.

It's Flax lignans's way of eating

It has existed in human history for more than five thousand years. Flax lignans belongs to seed class and grows all over the world. However, it is superior to those produced in cold regions.

This small reddish-brown fruit has a strong nutty flavor, N-Acetylneuraminic Acid even in baked goods. In fact, in many Parts of Europe, bakers often use this grain in almost all foods, such as biscuits, cakes, breads, etc.

Remember to grind the grain to get the best results. If they Gardenia Yellow were whole, they would be expelled without digestion.

Ease of cooking: Easy.

The grain has a hard shell Ginkgo Biloba Extract and must be partially crushed or ground (using a coffee grinder or blender) to release its nutrients. Crushed or ground fruit that can be added to bread or muffins or on top of yogurt or cereal products.

The chemical composition of Flax lignans

Seeds contain 30 ~ 48% fat, 18 ~ 33% protein, 5 ~ 12% viscosity, 12 ~ 26% sugar, Mangiferin organic acids and vitamins. In addition, there is a small amount of cyanogen namely linosin. Immature seeds contain starch and Gardenia Yellow disappear when ripe.

Flax lignans oil is a yellow liquid pressed at room temperature. It is gas specific and has a light taste. In the air, the quality gradually thickens, the color deepens, Capsicum Oleoresin and the gas and taste become stronger. The main components of the oil are linolenic acid 21 ~ 45%, linoleic acid 25 ~ 59%, oleic acid 15 ~ 20%, palmitic acid, stearic acid and other glycerides. In addition, it also contains alkyl ferulic acid.

The role of Flax lignans

1. Cure the wind disease, all over the body itch rash: Gardenia Yellow, burdock seed, wolfberry fruit, cranberry two half (with stir-fry, so that the smoke is degree), bittersweet two, fructus trichosanthis root, wind-proof (Mangiferin) half, white tribulus half. On eight taste, with pestle for the end, every 15 money medicine, into light powder two money, a place mix well. Each service - Capsicum Oleoresin end, tea, hollow, noon, linlie each a service. Five, seven days after taking the medicine, before the teeth gap, out of stinking yellow saliva, all over pain, after the convenience of pus and blood, this is the root of the disease. (Boji Fang)

2. Treatment of hair loss of fat overflow: fresh willow twigs, Flax lignans seed and one or two each. A decoction. (Jiangxi Chinese Herbal Medicine)

3. Treatment of cough and asthma: flaxseed, Wendan peel, decoction. (Jiangxi Chinese Herbal Medicine)

This is the power of the Flax lignans

Traditional Chinese medicine Flax lignans seed, alias also called linseed, flax kernel and so on. It is the dry and mature seed of the flax plant of linaceae. Plants are harvested when fruits are ripe in the autumn, dried, seeds laid, impurities removed, and then dried. This product is Mangiferin oval, one end is obtuse, the other end is pointed and slightly inclined, the length is 4 ~ 6mm, the width is 2 ~ 3mm. The surface is reddish-brown or taupe, smooth and shiny, the umbilicus is at the concave of the tip; The ridge is light brown, on one margin. Seed coat thin, endosperm brown, membranous, cotyledon 2, yellow-white, oily rich. Gardenia Yellow is odorless and has a bean-like smell when chewed.

Moisten bowel to aperient, raise blood dispel wind. For dryness and constipation; The elderly skin dry scaly, allergic dermatitis, itchy skin; Sores form eczema.

"Ben Cao Tu Jing" : "Treatment of wind sores and ringworm."

South Yunnan Herb: "Treatment of tuberculosis."

Chinese medicinal Materials Manual: "Ginkgo Biloba Extract, detoxification analgesia. Cure enteric heat, erysipelas."

"Medicine" : "Cure lung carbuncle vomit pus and blood."

"Commonly used Folk Herbs in Kunming" : "Seeds and roots: Smooth liver, smooth qi and clear intestines. For orchitis, hernia, chronic hepatitis, headache, constipation."

[Usage and dosage] For internal use: Fried soup, 3 ~ 5 yuan; Or powder. External use: tamping or decocting water.