Antibacterial antiviral: has a wider antibacterial effect, but in vivo can be inactivated by proteins. In vitro test showed that have antiviral activity, and gland for vaccinia virus inhibition is stronger, followed by polio Ⅰ and vice Caffeic Acid flu viruses.
Anti-snake venom: 20 micrograms of diamondback venom phosphodiesterase can be completely inhibited at a dose of 3 micrograms of caffeic acid.
Other effects: When oral or intraperitoneal injection, Bitter Melon Extract caffeic acid can improve the central excitability of rats; Oral administration can increase the amount of hydrochloric acid in the human stomach and slow the pulse. It can enhance uterine tension, which can be antagonized by papaverine, but not atropine. It can increase the secretion of bile in rats. It has the effect of increasing white blood cells, hemostasis and inactivating vitamin B1. It can inhibit the formation of lipid peroxides in the homogenate of rat brain. Flax lignans has the effect of shortening blood coagulation and bleeding time.
Toxicity: LD50 was 1583mg/kg by intraperitoneal injection. The Mangiferin was given intravenous injection of 14mg/kg/ day for 10 consecutive days, and no pathological changes were found in the heart, liver, renal function and anatomical microscopic examination.
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